Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323517 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL142445 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL8897656 | 0.82 | CTRB1 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1279658 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Carbamic Acid SCHEMBL28871401 | 0.78 | CYP2C19 (0.44) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL37382 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL4478397 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL31729909 | 0.77 | KMT2A (0.48) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL6363978 | 0.76 | CCNE1 (0.42) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL9942943 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307427-B3 | PROCESS FOR THE CYANATION OF ALDEHYDES | KING S COLLEGE LONDON (GB) | 2009-04-29 | — | — | EP | disclosed |
| US-7314844-B2 | Process for the cyanation aldehydes | KING'S COLLEGE LONDON (GB) | 2008-01-01 | — | — | US | disclosed |
| WO-2007093764-A1 | PROCESS FOR THE CYANATION OF IMINES | NPIL PHARMACEUTICALS (UK) LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
| EP-1307427-B1 | PROCESS FOR THE CYANATION OF ALDEHYDES | KING S COLLEGE LONDON (GB) | 2006-04-12 | — | — | EP | disclosed |
| US-20050192454-A1 | Process for the cyanation aldehydes | NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS AND KING'S COLLEGE LONDON | 2005-09-01 | — | — | US | disclosed |
| US-6897332-B2 | Process for the cyanation of aldehydes | NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS (RU) | 2005-05-24 | — | — | US | disclosed |
| EP-1511565-A2 | CATALYST AND PROCESS FOR THE CYANATION OF ALDEHYDES | KING'S COLLEGE LONDON (GB) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099435-A2 | CATALYST AND PROCESS FOR THE CYANATION OF ALDEHYDES | KING'S COLLEGE LONDON (GB) | 2003-12-04 | — | — | WO | disclosed |
| US-20030199706-A1 | Process for the cyanation of aldehydes | NESMEY ANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS | 2003-10-23 | — | — | US | disclosed |
| EP-1307427-A2 | PROCESS FOR THE CYANATION OF ALDEHYDES | King's College London (GB) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010095-A2 | PROCESS FOR THE CYANATION OF ALDEHYDES | KING'S COLLEGE LONDON, AN INSTITUTION INCORPORATED BY ROYAL CHARTER (GB) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199706-A1 | Process for the cyanation of aldehydes | CPN1, CRBN, NCL | ALDH1A1 459/4885TDP1 2059/4885MAPK1 3772/4885 |
| US-20050192454-A1 | Process for the cyanation aldehydes | CA4, CA9, CA12 | ALDH1A1 328/4885TDP1 3105/4885MAPK1 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.