Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045457 | 0.96 | FKBP1A (0.39) | FKBP1ASMYD3 | |
| SCHEMBL4045390 | 0.87 | HPGD (0.41) | FKBP1A | |
| SCHEMBL4038231 | 0.87 | SMYD3 (0.39) | FKBP1ASMYD3 | |
| SCHEMBL4043420 | 0.86 | SMYD3 (0.39) | FKBP1ASMYD3 | |
| SCHEMBL4044950 | 0.86 | DPP4 (0.39) | FKBP1ASMYD3 | |
| SCHEMBL4043887 | 0.85 | DPP4 (0.46) | FKBP1A | |
| SCHEMBL4040220 | 0.84 | DPP4 (0.41) | FKBP1A | |
| SCHEMBL4042575 | 0.84 | DPP4 (0.41) | — | |
| SCHEMBL4047936 | 0.84 | C3AR1 (0.39) | — | |
| SCHEMBL4044930 | 0.84 | DPP4 (0.38) | FKBP1ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | FKBP1A 1519/4885SMYD3 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.