Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.34 |
| ▸ | HTR3B | O95264 | 4/20 | 0.34 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046318 | 0.94 | CTSK (0.47) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL4048075 | 0.93 | CTSK (0.51) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL6242529 | 0.92 | CTSK (0.43) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL4046272 | 0.89 | CTSK (0.46) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL4045086 | 0.89 | CTSK (0.42) | CTSKCTSSCTSBMEN1KMT2A | |
| SCHEMBL4046827 | 0.88 | CTSK (0.48) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL4045201 | 0.88 | CTSK (0.46) | CTSKCTSSHPGDSCTSBACKR3 | |
| SCHEMBL4039365 | 0.87 | CTSK (0.59) | CTSKCTSSHPGDSCTSBCHRNA7 | |
| SCHEMBL4042035 | 0.85 | CTSK (0.47) | CTSKCTSSHPGDSCTSB | |
| SCHEMBL4040890 | 0.84 | CTSK (0.49) | CTSKCTSSHPGDSCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | CTSK 2/4885CTSS 3/4885HPGDS 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.