Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.36 |
| ▸ | HTR3B | O95264 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041636 | 0.92 | CTSK (0.47) | CTSKCTSSCHRNA7HTR3EHTR3B | |
| SCHEMBL6211260 | 0.91 | CTSK (0.39) | CTSKCTSSCHRNA7P2RY12PREP | |
| SCHEMBL4046677 | 0.89 | CTSK (0.34) | CTSKCTSSP2RY12 | |
| SCHEMBL6274440 | 0.88 | CTSK (0.48) | CTSKCTSSP2RY12PREPFAP | |
| SCHEMBL4046318 | 0.86 | CTSK (0.47) | CTSKCTSSCHRNA7HTR3EHTR3B | |
| SCHEMBL4048075 | 0.85 | CTSK (0.51) | CTSKCTSSCHRNA7HTR3EHTR3B | |
| SCHEMBL4040062 | 0.84 | CTSK (0.40) | CTSKCTSSCTSBP2RY12HPGDS | |
| SCHEMBL4045150 | 0.84 | CTSK (0.44) | CTSKCTSSP2RY12PREPFAP | |
| SCHEMBL4039142 | 0.83 | CTSK (0.45) | CTSKCTSSP2RY12PREPFAP | |
| SCHEMBL6240734 | 0.83 | CTSK (0.39) | CTSKCTSSP2RY12PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |