Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | PPARA | Q07869 | 11/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040101 | 0.88 | PPARA (0.48) | PPARGPPARACYP2C19RIPK1PPARD | |
| SCHEMBL3484675 | 0.85 | RIPK1 (0.41) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL22209208 | 0.78 | PPARG (0.74) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL4036404 | 0.78 | PPARG (0.66) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL4033120 | 0.77 | MMP2 (0.49) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL30054133 | 0.77 | HRH1 (0.60) | PPARAKMT2ARIPK1SLC6A2SLC6A4 | |
| SCHEMBL11545612 | 0.77 | PPARA (0.71) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL561362 | 0.77 | HRH1 (0.60) | PPARAKMT2ARIPK1SLC6A2SLC6A4 | |
| SCHEMBL11738947 | 0.76 | PPARG (0.72) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL247466 | 0.75 | PPARA (0.68) | PPARGPPARACYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |