Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041637 | 0.88 | PPARG (0.54) | PPARAPPARDPPARGKDM4EALDH1A1 | |
| SCHEMBL3484445 | 0.86 | SLC1A5 (0.40) | PPARAPPARDPPARGKDM4ERIPK1 | |
| SCHEMBL4036545 | 0.79 | PPARG (0.60) | PPARAPPARDPPARGPTPN7DUSP3 | |
| SCHEMBL6955048 | 0.78 | SLC6A2 (0.50) | ALDH1A1RIPK1 | |
| SCHEMBL4037839 | 0.77 | PPARG (0.44) | PPARAPPARDPPARGPTPN7DUSP3 | |
| SCHEMBL3484675 | 0.74 | RIPK1 (0.41) | PPARAPPARGRIPK1SLC1A5CYP2C9 | |
| SCHEMBL561362 | 0.73 | HRH1 (0.60) | PPARARIPK1 | |
| SCHEMBL30054133 | 0.73 | HRH1 (0.60) | PPARARIPK1 | |
| SCHEMBL7988206 | 0.73 | PPARA (0.55) | PPARAPPARDPPARGKDM4EALDH1A1 | |
| SCHEMBL4040746 | 0.72 | PPARG (0.55) | PPARAPPARDPPARGPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |