Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035524 | 0.79 | NPC1 (0.62) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL7931752 | 0.78 | KMT2A (0.49) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL4034766 | 0.76 | NLRP3 (0.51) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL4041685 | 0.75 | POLB (0.62) | LMNATDP1SMN1; SMN2KMT2AHTT | |
| SCHEMBL7692175 | 0.73 | EGLN1 (0.64) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL16879461 | 0.73 | CA1 (0.49) | KMT2AHTTRAB9ACA1CA2 | |
| SCHEMBL9311156 | 0.73 | KDM4E (0.57) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL8342468 | 0.73 | KDM4E (0.60) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL8342587 | 0.73 | ALOX12 (1.00) | LMNATDP1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL16603426 | 0.73 | ALOX12 (0.52) | LMNATDP1SMN1; SMN2ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |