Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 4/20 | 0.61 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CA3 | P07451 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL4031818 | 0.93 | ALDH1A1 (0.59) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL11405408 | 0.87 | CA2 (0.64) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL8756380 | 0.83 | GLA (0.64) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL7884546 | 0.81 | KDM4E (0.65) | CA12CA9CA2ALDH1A1MAOB | |
| SCHEMBL15842248 | 0.81 | ALDH1A1 (0.63) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL10305766 | 0.81 | ALDH1A1 (0.63) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL18474355 | 0.80 | CA9 (0.65) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL17768961 | 0.80 | ALDH1A1 (0.61) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL2689564 | 0.80 | CA12 (0.64) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL8787053 | 0.80 | ALDH1A1 (0.61) | CA12CA9CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478143-B | Donepezil derivative, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-05-09 | — | — | CN | claimed |
| CN-116478143-A | Donepezil derivative, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-07-25 | — | — | CN | claimed |
| CN-116478143-B | Donepezil derivative, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-05-09 | — | — | CN | disclosed |
| CN-116478143-A | Donepezil derivative, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-07-25 | — | — | CN | disclosed |
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | US | disclosed |
| EP-1392680-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20040039019-A1 | Selected anthranilaminde pyridinamides and their use as pharmaceutical agents | SCHERING AG (DE) | 2004-02-26 | — | — | US | disclosed |
| WO-2002090352-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |
| US-4287126-A | (2-Oxo-2H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives | WARNER-LAMBERT COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4210758-A | 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides | WARNER-LAMBERT COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4046769-A | 4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-2-carboxylic acids and esters | WARNER-LAMBERT COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | AASDHPPT, CA13, CA12 | CA12 3/4885CA9 13/4885CA2 10/4885 |
| US-20040039019-A1 | Selected anthranilaminde pyridinamides and their use as pharmaceutical agents | KDR, FLT1, FLT4 | CA12 3633/4885CA9 2684/4885CA2 1354/4885 |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | CA12 3/4885CA9 13/4885CA2 10/4885 |
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | FLT4, KDR, FLT1 | CA12 4768/4885CA9 4599/4885CA2 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.