SCHEMBL4041861

SCHEMBL4041861

CCCCCCOC(CC(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MMP9 P14780 2/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.45
FFAR1 O14842 3/20 0.45
NAAA Q02083 2/20 0.44
CYSLTR2 Q9NS75 3/20 0.44
CYSLTR1 Q9Y271 3/20 0.44
PLA2G4B P0C869 1/20 0.44
MMP2 P08253 1/20 0.44
MMP12 P39900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1165785 0.98 NPC1 (0.48) NPC1RAB9ASMN1; SMN2MMP9MMP8
SCHEMBL27663465 0.94 FFAR1 (0.50) SMN1; SMN2MMP9MMP8MMP13FFAR1
SCHEMBL21624573 0.88 LMNA (0.53) NPC1RAB9ASMN1; SMN2MMP9MMP8
SCHEMBL4298983 0.87 FFAR1 (0.49) SMN1; SMN2LMNAALDH1A1FFAR1
SCHEMBL29033399 0.83 NPC1 (0.46) NPC1RAB9ASMN1; SMN2LMNATSHR
SCHEMBL27396397 0.82 NPC1 (0.44) NPC1RAB9ASMN1; SMN2LMNATSHR
SCHEMBL4759813 0.81 FFAR1 (0.44) SMN1; SMN2FFAR1
SCHEMBL28042429 0.81 NPC1 (0.43) NPC1RAB9ASMN1; SMN2LMNATSHR
SCHEMBL28042226 0.81 NPC1 (0.43) NPC1RAB9ASMN1; SMN2LMNATSHR
SCHEMBL28042428 0.81 NPC1 (0.43) NPC1RAB9ASMN1; SMN2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-20260014169-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE AZURITY PHARMACEUTICALS, INC. (US) 2026-01-15 US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 US disclosed
WO-2025054607-A1 COMPOSITIONS AND METHODS FOR TREATING SARCOPENIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-13 WO disclosed
US-20250032508-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SLAYBACK PHARMA LLC (US) 2025-01-30 US disclosed
US-12138271-B2 Pharmaceutical compositions of testosterone SLAYBACK PHARMA LLC (US) 2024-11-12 US disclosed
US-20230248742-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SLAYBACK PHARMA LLC (US) 2023-08-10 US disclosed
US-11642355-B2 Pharmaceutical compositions of testosterone SLAYBACK PHARMA LLC (US) 2023-05-09 US disclosed
US-20220202830-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SLAYBACK PHARMA LLC (US) 2022-06-30 US disclosed
US-11311554-B2 Pharmaceutical compositions of testosterone SLAYBACK PHARMA LLC (US) 2022-04-26 US disclosed
US-20190307772-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SLAYBACK PHARMA LLC (US) 2019-10-10 US disclosed
EP-2068840-A2 HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM LAB International SRL (US) 2009-06-17 EP disclosed
EP-2049087-A2 HYDROPHILIC ABUSE DETERRENT DELIVERY SYSTEM LAB International SRL (US) 2009-04-22 EP disclosed
WO-2008011595-A9 HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM LAB INTERNAT SRL (US) 2008-03-06 WO disclosed
WO-2008011595-A2 HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM LAB INTERNATIONAL SRL (US) 2008-01-24 WO disclosed
WO-2008011596-A2 HYDROPHILIC ABUSE DETERRENT DELIVERY SYSTEM LAB INTERNATIONAL SRL (US) 2008-01-24 WO disclosed
EP-1727520-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2006-12-06 EP disclosed
WO-2005055983-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2005-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014169-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SHBG, CYP17A1, AR NPC1 348/4885RAB9A 3325/4885SMN1; SMN2 855/4885
US-20230248742-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SHBG, CYP17A1, NR5A1 NPC1 1150/4885RAB9A 3930/4885SMN1; SMN2 833/4885
US-11311554-B2 Pharmaceutical compositions of testosterone SHBG, CYP17A1, NR5A1 NPC1 966/4885RAB9A 4150/4885SMN1; SMN2 1149/4885
US-12138271-B2 Pharmaceutical compositions of testosterone SHBG, CYP17A1, NR5A1 NPC1 1150/4885RAB9A 3930/4885SMN1; SMN2 833/4885
US-11642355-B2 Pharmaceutical compositions of testosterone SHBG, CYP17A1, NR5A1 NPC1 961/4885RAB9A 4138/4885SMN1; SMN2 1127/4885
US-20190307772-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SHBG, CYP17A1, NR5A1 NPC1 966/4885RAB9A 4150/4885SMN1; SMN2 1149/4885
US-20220202830-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SHBG, CYP17A1, NR5A1 NPC1 961/4885RAB9A 4138/4885SMN1; SMN2 1127/4885
US-20250032508-A1 PHARMACEUTICAL COMPOSITIONS OF TESTOSTERONE SHBG, CYP17A1, NR5A1 NPC1 1150/4885RAB9A 3930/4885SMN1; SMN2 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.