SCHEMBL4298983

SCHEMBL4298983

CCCOC(CC(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.43
GABBR2 O75899 1/20 0.43
GABBR1 Q9UBS5 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27663465 0.90 FFAR1 (0.50) FFAR1SMN1; SMN2
SCHEMBL1165785 0.89 NPC1 (0.48) FFAR1SMN1; SMN2LMNAALDH1A1
SCHEMBL27907309 0.88 GABBR2 (0.44) FFAR1GABBR2GABBR1
SCHEMBL4041861 0.87 NPC1 (0.49) FFAR1SMN1; SMN2LMNAALDH1A1
SCHEMBL1670315 0.86 FFAR1 (0.62) FFAR1
SCHEMBL7507485 0.85 HPGD (0.49) FFAR1GABBR2GABBR1ALDH1A1
SCHEMBL9554333 0.82 RIPK1 (0.44) FFAR1GABBR2GABBR1
SCHEMBL27142032 0.82 SCN1A (0.58) FFAR1GABBR2GABBR1
Hydrochloric Acid SCHEMBL28602407 0.81 SCN1A (0.57) FFAR1GABBR2GABBR1
SCHEMBL24925628 0.80 GSR (0.47) SMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200155568-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2020-05-21 US disclosed
US-10555952-B2 Pharmaceutical compositions and methods for anesthesiological applications MELT PHARMACEUTICALS, INC. (US) 2020-02-11 US disclosed
US-20180303847-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2018-10-25 US disclosed
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS LABORATORIOS SALVAT, S.A. (ES) 2009-04-02 US disclosed
US-7423172-B2 Tyrosine derivatives as PPAR-γ-modulators LABORATORIOS SALVAT, S.A. (ES) 2008-09-09 US disclosed
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators LABORATORIES SALVAT, S.A. (ES) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS PPARG, PPARD, TYRO3 FFAR1 67/4885SMN1; SMN2 4621/4885LMNA 4048/4885
US-10555952-B2 Pharmaceutical compositions and methods for anesthesiological applications GRIN2B, GRIN3A, GABRA5 FFAR1 1030/4885SMN1; SMN2 3318/4885LMNA 2707/4885
US-20200155568-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN2B, GRIN3A, GABRA5 FFAR1 1030/4885SMN1; SMN2 3318/4885LMNA 2707/4885
US-20180303847-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN2B, GRIN3A, GABRA5 FFAR1 1030/4885SMN1; SMN2 3318/4885LMNA 2707/4885
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators PPARG, PPARD, PPARA FFAR1 107/4885SMN1; SMN2 4448/4885LMNA 3937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.