Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663465 | 0.84 | FFAR1 (0.50) | FFAR1SMN1; SMN2 | |
| SCHEMBL1165785 | 0.83 | NPC1 (0.48) | FFAR1SMN1; SMN2 | |
| SCHEMBL27907309 | 0.81 | GABBR2 (0.44) | FFAR1GABBR2GABBR1 | |
| SCHEMBL4041861 | 0.81 | NPC1 (0.49) | FFAR1SMN1; SMN2 | |
| SCHEMBL4298983 | 0.80 | FFAR1 (0.49) | FFAR1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL7507485 | 0.79 | HPGD (0.49) | FFAR1GABBR2GABBR1 | |
| SCHEMBL3702042 | 0.78 | GABBR2 (0.47) | FFAR1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL27142032 | 0.76 | SCN1A (0.58) | FFAR1GABBR2GABBR1 | |
| SCHEMBL9554333 | 0.76 | RIPK1 (0.44) | FFAR1GABBR2GABBR1 | |
| SCHEMBL27785716 | 0.76 | FFAR1 (0.43) | FFAR1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945613-A1 | NOVEL 1 -BENZYL-4-PIPERIDINAMINES THAT ARE USEFUL IN THE TREATMENT OF COPD AND ASTHMA | AstraZeneca AB (SE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007053082-A1 | NOVEL 1 -BENZYL-4-PIPERIDINAMINES THAT ARE USEFUL IN THE TREATMENT OF COPD AND ASTHMA | ASTRAZENECA AB (SE) | 2007-05-10 | — | — | WO | disclosed |