Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165789 | 0.98 | TSHR (0.46) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL27663466 | 0.94 | TSHR (0.45) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL4298978 | 0.89 | LMNA (0.46) | TSHRLMNAALDH1A1CYP3A4MEN1 | |
| SCHEMBL28598274 | 0.86 | TSHR (0.49) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL9623042 | 0.84 | TSHR (0.47) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| Citric Acid SCHEMBL7430817 | 0.83 | KDM4E (0.45) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL4759819 | 0.83 | KDM4E (0.43) | LMNAALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL9482513 | 0.82 | TSHR (0.40) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL9068153 | 0.81 | TSHR (0.47) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL11021679 | 0.80 | ALDH1A1 (0.46) | LMNAALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-2068840-A2 | HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM | LAB International SRL (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2049087-A2 | HYDROPHILIC ABUSE DETERRENT DELIVERY SYSTEM | LAB International SRL (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008011595-A9 | HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM | LAB INTERNAT SRL (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008011596-A2 | HYDROPHILIC ABUSE DETERRENT DELIVERY SYSTEM | LAB INTERNATIONAL SRL (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008011595-A2 | HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM | LAB INTERNATIONAL SRL (US) | 2008-01-24 | — | — | WO | disclosed |
| EP-1727520-A2 | METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS | MEDCRYSTALFORMS, LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005055983-A2 | METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS | MEDCRYSTALFORMS, LLC (US) | 2005-06-23 | — | — | WO | disclosed |