Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042992 | 0.84 | CTSK (0.39) | CTSKALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL4048376 | 0.83 | CTSK (0.51) | CTSKALDH1A1 | |
| SCHEMBL4044247 | 0.81 | CTSK (0.39) | CTSKALDH1A1POLB | |
| SCHEMBL4044693 | 0.81 | CTSK (0.42) | CTSKALDH1A1NPC1 | |
| SCHEMBL4043459 | 0.80 | CTSK (0.41) | CTSKALDH1A1 | |
| SCHEMBL4042281 | 0.79 | CTSK (0.44) | CTSKF10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4050761 | 0.78 | PIK3CD (0.42) | CTSKALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4040766 | 0.78 | CTSK (0.40) | CTSKALDH1A1HPGD | |
| SCHEMBL4042191 | 0.78 | CTSK (0.36) | CTSK | |
| SCHEMBL4228919 | 0.78 | CTSK (0.38) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |