Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048376 | 0.86 | CTSK (0.51) | CTSKALDH1A1 | |
| SCHEMBL4044693 | 0.85 | CTSK (0.42) | CTSKKMT2ADPP8DPP9ALDH1A1 | |
| SCHEMBL4042992 | 0.84 | CTSK (0.39) | CTSKPKMALDH1A1POLB | |
| SCHEMBL4043459 | 0.83 | CTSK (0.41) | CTSKALDH1A1 | |
| SCHEMBL4042279 | 0.81 | CTSK (0.37) | CTSKALDH1A1POLB | |
| SCHEMBL4040766 | 0.81 | CTSK (0.40) | CTSKALDH1A1 | |
| SCHEMBL4050761 | 0.81 | PIK3CD (0.42) | CTSKDPP4DPP8DPP9ALDH1A1 | |
| SCHEMBL4049285 | 0.81 | CTSK (0.41) | CTSKMEN1KMT2A | |
| SCHEMBL4044250 | 0.80 | CTSK (0.49) | CTSKMEN1PKMKMT2ADPP4 | |
| SCHEMBL4228919 | 0.79 | CTSK (0.38) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |