Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 16/20 | 0.43 |
| ▸ | CTSS | P25774 | 15/20 | 0.43 |
| ▸ | CTSK | P43235 | 15/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041994 | 0.90 | CTSS (0.39) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4045653 | 0.90 | CTSS (0.38) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4046866 | 0.89 | CTSK (0.43) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4051200 | 0.89 | CTSK (0.44) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4046503 | 0.89 | CTSL (0.37) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4047616 | 0.88 | CTSL (0.46) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4046543 | 0.87 | KCNQ1 (0.38) | CTSLCTSSCTSVGCK | |
| SCHEMBL4041473 | 0.86 | CTSS (0.41) | CTSLCTSSCTSKCTSVUSP30 | |
| SCHEMBL4039394 | 0.86 | CTSL (0.42) | CTSLCTSSCTSKCTSVCTSB | |
| SCHEMBL4047132 | 0.85 | CTSS (0.39) | CTSLCTSSCTSKCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |