SCHEMBL40426

SCHEMBL40426

CC(C)(c1ccc(N2COc3ccccc3C2)cc1)c1ccc(N2COc3ccccc3C2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.38
NPC1 O15118 5/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 6/20 0.36
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 1/20 0.36
BACE1 P56817 1/20 0.36
HSD17B3 P37058 1/20 0.33
VDR P11473 1/20 0.33
TSHR P16473 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
ESR2 Q92731 1/20 0.33
HPGD P15428 1/20 0.31
OXTR P30559 1/20 0.31
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13823374 0.97 ALDH1A1 (0.38) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL13933836 0.94 TSHR (0.40) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL15358723 0.92 NPC1 (0.42) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL13203365 0.92 RAB9A (0.40) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL20932611 0.87 MEN1 (0.47) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL13843142 0.86 ESR1 (0.36) ESR1ESR2ALOX15
SCHEMBL13550842 0.85
SCHEMBL12162755 0.83 TSHR (0.47) RAB9ANPC1KDM4EMEN1GAA
SCHEMBL10015232 0.82 NPC1 (0.41) RAB9ANPC1KDM4EMEN1KMT2A
SCHEMBL40405 0.82 MAPT (0.41) RAB9ANPC1KDM4EMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159693-A1 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS KANEKA AEROSPACE LLC (US) 2023-05-25 US disclosed
US-20230159693-A1 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS KANEKA AEROSPACE LLC (US) 2023-05-25 US disclosed
EP-2969446-B1 PREPREG CURING PROCESS FOR PREPARING COMPOSITES HAVING SUPERIOR SURFACE FINISH AND HIGH FIBER CONSOLIDATION Henkel IP & Holding GmbH (DE) 2022-12-28 EP disclosed
US-20210102035-A1 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS KANEKA AEROSPACE LLC (US) 2021-04-08 US disclosed
EP-2890744-B1 FLAME-RETARDANT BENZOXAZINE-CONTAINING COMPOSITION HENKEL AG & CO KGAA (DE) 2021-02-17 EP disclosed
EP-2231743-B1 CURABLE BENZOXAZINE MACROMONOMERS, THEIR PREPARATION AND CURED PRODUCTS THEREOF HENKEL AG & CO KGAA (DE) 2019-05-22 EP disclosed
US-20170183450-A1 CATIONICALLY CURABLE BENZOXAZINE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2017-06-29 US disclosed
US-20170183450-A1 CATIONICALLY CURABLE BENZOXAZINE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2017-06-29 US disclosed
US-9427943-B2 Prepreg curing process for preparing composites having superior surface finish and high fiber consolidation Henkel IP & Holding GmbH (DE) 2016-08-30 US disclosed
US-9427943-B2 Prepreg curing process for preparing composites having superior surface finish and high fiber consolidation Henkel IP & Holding GmbH (DE) 2016-08-30 US disclosed
US-20080076886-A1 Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening LOCTITE (R&D) LIMITED 2008-03-27 US disclosed
US-20080076886-A1 Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening LOCTITE (R&D) LIMITED 2008-03-27 US disclosed
US-7312534-B2 Interlayer dielectric and pre-applied die attach adhesive materials HENKEL CORPORATION (US) 2007-12-25 US disclosed
US-7312534-B2 Interlayer dielectric and pre-applied die attach adhesive materials HENKEL CORPORATION (US) 2007-12-25 US disclosed
US-20070278683-A1 Interlayer Dielectric and Pre-Applied Die Attach Adhesive Materials HENKEL CORPORATION (US) 2007-12-06 US disclosed
US-20070278683-A1 Interlayer Dielectric and Pre-Applied Die Attach Adhesive Materials HENKEL CORPORATION (US) 2007-12-06 US disclosed
US-20070129509-A1 Curable compositions HENKEL CORPORATION 2007-06-07 US disclosed
US-20070129509-A1 Curable compositions HENKEL CORPORATION 2007-06-07 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129509-A1 Curable compositions CBX4, CBX7, KDM5C RAB9A 4196/4885NPC1 4543/4885KDM4E 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.