Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 10/20 | 0.33 |
| ▸ | CTSS | P25774 | 9/20 | 0.33 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044802 | 0.93 | ALDH1A1 (0.35) | CTSKALDH1A1CTSSMMP13MMP1 | |
| SCHEMBL4044566 | 0.91 | CTSK (0.42) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4039264 | 0.90 | CTSK (0.40) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4042338 | 0.89 | CTSK (0.43) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4046924 | 0.85 | CTSK (0.40) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4045577 | 0.85 | CTSK (0.41) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4042987 | 0.85 | CTSK (0.41) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4049409 | 0.85 | CTSK (0.42) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4042329 | 0.85 | CTSK (0.40) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4048017 | 0.84 | CTSK (0.34) | CTSKMMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |