Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 8/20 | 0.34 |
| ▸ | CTSS | P25774 | 8/20 | 0.34 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043638 | 0.93 | ALDH1A1 (0.35) | CTSKHCRTR2HSD17B10CHRNB2CHRNA7 | |
| SCHEMBL4037989 | 0.93 | CTSK (0.42) | CTSKKMT2AHCRTR2HSD17B10CHRNB2 | |
| SCHEMBL4042672 | 0.91 | CTSK (0.41) | CTSKKMT2AHSD17B10CHRNB2CHRNA7 | |
| SCHEMBL4039264 | 0.90 | CTSK (0.40) | CTSKKMT2AHSD17B10ALDH1A1CTSL | |
| SCHEMBL4042338 | 0.90 | CTSK (0.43) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4042987 | 0.86 | CTSK (0.41) | CTSKKMT2AHSD17B10ALDH1A1CTSL | |
| SCHEMBL4045577 | 0.86 | CTSK (0.41) | CTSKKMT2AHSD17B10ALDH1A1CTSL | |
| SCHEMBL4044312 | 0.86 | CTSK (0.40) | CTSKKMT2AHCRTR2HSD17B10KCNQ1 | |
| SCHEMBL4043291 | 0.85 | CTSK (0.40) | CTSKKMT2AHSD17B10ALDH1A1CTSL | |
| SCHEMBL4049190 | 0.85 | CTSK (0.40) | CTSKKMT2AHCRTR2HSD17B10CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |