SCHEMBL4044005

SCHEMBL4044005

Oc1ccc(Oc2cc(Cl)cc(Cl)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
ESR1 P03372 1/20 0.64
ESR2 Q92731 1/20 0.64
LTA4H P09960 5/20 0.54
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
MAPK1 P28482 1/20 0.50
HSP90AA1 P07900 1/20 0.48
PARP10 Q53GL7 1/20 0.45
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10875292 0.86 ESR1 (0.52) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL2960969 0.86 MEN1 (0.52) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL9657433 0.83 MEN1 (0.74) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL989610 0.83 MEN1 (0.74) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL16551547 0.83 MEN1 (0.82) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL11222220 0.81 HSP90AA1 (0.52) MEN1KMT2AESR1ESR2HSP90AA1
SCHEMBL8966889 0.81 LTA4H (0.59) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL3175106 0.80 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL7811939 0.80 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL18198 0.80 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 EP disclosed
US-6995110-B2 Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-07 US disclosed
US-20040077487-A1 Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-22 US disclosed
EP-1380342-A1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-01-14 EP disclosed
US-4625048-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1986-11-25 US disclosed
EP-0072475-B1 CARBAMIC ESTERS, PREPARATION THEREOF, PESTICIDAL COMPOSITIONS ON THE BASIS OF THESE COMPOUNDS AND THEIR USE IN COMBATING PESTS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1986-08-20 EP disclosed
US-4607051-A Carbamic acid compound and use as a pesticide HOFFMANN-LA ROCHE INC. (US) 1986-08-19 US disclosed
US-4413010-A Carbamic acid esters and use as pesticides HOFFMANN-LA ROCHE INC. (US) 1983-11-01 US disclosed
US-4391995-A 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
EP-0072475-A2 Carbamic esters, preparation thereof, pesticidal compositions on the basis of these compounds and their use in combating pests F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-02-23 EP disclosed
US-4301295-A ANTILIPEMIC AND ANTICHOLESTEROL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-17 US disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed
US-4238626-A ANTICHOLESTEROL AND ANTILIPEMIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed