Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047634 | 0.89 | CTSL (0.39) | CTSKCTSSCTSLPREPFAP | |
| SCHEMBL4046569 | 0.88 | CTSK (0.35) | CTSKCTSSCTSLELANE | |
| SCHEMBL4044148 | 0.87 | CTSK (0.42) | CTSKCTSSCTSL | |
| SCHEMBL4041626 | 0.85 | CTSK (0.34) | CTSKCTSSCTSLMAPK1ALDH1A1 | |
| SCHEMBL4049243 | 0.85 | CTSK (0.44) | CTSKCTSSCTSLRBP4ELANE | |
| SCHEMBL4051346 | 0.84 | CTSK (0.38) | CTSKCTSSALDH1A1L3MBTL1 | |
| SCHEMBL4050717 | 0.83 | CTSK (0.44) | CTSKCTSSCTSLRBP4ELANE | |
| SCHEMBL4052140 | 0.81 | HSD17B10 (0.36) | CTSKALDH1A1HSD17B10 | |
| SCHEMBL4045645 | 0.80 | SMYD3 (0.34) | CTSKCTSSCTSLALDH1A1 | |
| SCHEMBL4051458 | 0.80 | CTSK (0.36) | CTSKPREPFAPELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |