Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040451 | 0.93 | CTSK (0.41) | CTSKCTSSCTSLELANETGM2 | |
| SCHEMBL4042251 | 0.92 | CTSK (0.50) | CTSKCTSSCTSL | |
| SCHEMBL4041473 | 0.88 | CTSS (0.41) | CTSKCTSSCTSL | |
| SCHEMBL4037824 | 0.88 | CTSK (0.36) | CTSKCTSSCTSLELANE | |
| SCHEMBL4050717 | 0.87 | CTSK (0.44) | CTSKCTSSCTSLELANERBP4 | |
| SCHEMBL4051200 | 0.86 | CTSK (0.44) | CTSKCTSSCTSL | |
| SCHEMBL4044151 | 0.85 | CTSK (0.43) | CTSKCTSSCTSLELANERBP4 | |
| SCHEMBL4045469 | 0.84 | ELANE (0.37) | CTSKCTSSCTSLELANE | |
| SCHEMBL4048509 | 0.83 | CTSK (0.38) | CTSKELANE | |
| SCHEMBL4045843 | 0.82 | CTSK (0.43) | CTSKCTSSCTSLELANETGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |