Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 6/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044977 | 0.89 | KDM4E (0.41) | GPR35HSD17B10KDM4ENPC1ALDH1A1 | |
| SCHEMBL593799 | 0.72 | MAPT (0.53) | HSD17B10KDM4ENPC1ALDH1A1MAPK1 | |
| SCHEMBL6695055 | 0.71 | FABP3 (0.53) | HSD17B10KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL73952 | 0.71 | ALDH1A1 (0.47) | HSD17B10KDM4ENPC1ALDH1A1MAPK1 | |
| SCHEMBL2904866 | 0.70 | GPR35 (0.40) | GPR35HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4044343 | 0.69 | KDM4E (0.42) | GPR35KDM4EHTTPOLB | |
| SCHEMBL11418034 | 0.69 | DHODH (0.49) | GPR35KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL2493749 | 0.68 | ALDH1A1 (0.59) | HSD17B10KDM4EALDH1A1MAPTHTT | |
| SCHEMBL12171992 | 0.66 | NPC1 (0.53) | HSD17B10KDM4ENPC1ALDH1A1MAPK1 | |
| SCHEMBL487560 | 0.65 | ALDH1A1 (0.50) | HSD17B10KDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | claimed |
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | disclosed |