Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC26A3 | P40879 | 4/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044393 | 0.69 | GPR35 (0.39) | KDM4EGPR35HTTPOLB | |
| SCHEMBL2744483 | 0.67 | GRIK1 (0.54) | RXRARXRBMRGPRX4MEN1KMT2A | |
| SCHEMBL29004332 | 0.64 | CSNK2A2 (0.52) | RXRARXRBMRGPRX4GPR35MEN1 | |
| SCHEMBL9474035 | 0.61 | TSHR (0.60) | KDM4ESYKRXRARXRBMRGPRX4 | |
| SCHEMBL12566232 | 0.60 | GSK3B (0.44) | KDM4ERXRARXRB | |
| SCHEMBL2627825 | 0.60 | RXRA (0.68) | RXRARXRBRXRG | |
| SCHEMBL6248649 | 0.59 | LMNA (0.59) | HTT | |
| Alcohol SCHEMBL20953809 | 0.59 | RXRA (0.60) | RXRARXRBMRGPRX4HTTMEN1 | |
| SCHEMBL20021933 | 0.59 | BCL9 (0.53) | SYKKMT2ATHRATHRB | |
| SCHEMBL8736663 | 0.59 | CA12 (0.50) | KDM4EHTTMEN1KMT2ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | claimed |