Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 16/20 | 0.35 |
| ▸ | CTSL | P07711 | 13/20 | 0.35 |
| ▸ | CTSS | P25774 | 12/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050718 | 0.92 | CTSK (0.41) | CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL4044283 | 0.89 | CTSK (0.45) | CTSKCTSLCTSS | |
| SCHEMBL4047765 | 0.88 | PREP (0.35) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL6235917 | 0.88 | CTSK (0.46) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4048824 | 0.88 | CTSK (0.37) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4042961 | 0.88 | CTSK (0.36) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4043139 | 0.87 | ELANE (0.37) | PREPFAPCTSKELANEALDH1A1 | |
| SCHEMBL4051063 | 0.87 | SMYD3 (0.36) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4038257 | 0.87 | PREP (0.34) | PREPFAPCTSKELANEALDH1A1 | |
| SCHEMBL4045026 | 0.86 | CTSK (0.36) | PREPFAPCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463728-B1 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | disclosed |