Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.37 |
| ▸ | CTSL | P07711 | 15/20 | 0.37 |
| ▸ | CTSS | P25774 | 11/20 | 0.37 |
| ▸ | CTSB | P07858 | 5/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051812 | 0.93 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4048091 | 0.93 | HPGD (0.38) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4044711 | 0.90 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4045167 | 0.90 | ALDH1A1 (0.38) | PREPFAPNPC1RAB9A | |
| SCHEMBL4046863 | 0.88 | SMYD3 (0.35) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4049192 | 0.88 | CTSK (0.37) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4045026 | 0.88 | CTSK (0.36) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL4044689 | 0.88 | PREP (0.35) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4045022 | 0.87 | CTSK (0.35) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4040800 | 0.86 | PREP (0.36) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |