Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.46 |
| ▸ | CTSL | P07711 | 14/20 | 0.46 |
| ▸ | CTSS | P25774 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053232 | 0.89 | CTSK (0.48) | CTSKCTSLCTSSALDH1A1PREP | |
| SCHEMBL4044689 | 0.88 | PREP (0.35) | CTSKCTSLCTSSALDH1A1PREP | |
| SCHEMBL4041378 | 0.87 | CTSK (0.44) | CTSKCTSLCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL4040706 | 0.85 | CTSK (0.45) | CTSKCTSLCTSSALDH1A1PREP | |
| SCHEMBL4039999 | 0.85 | CTSK (0.54) | CTSKCTSLCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL4040873 | 0.85 | CTSK (0.41) | CTSKCTSLCTSSALDH1A1TSHR | |
| SCHEMBL4042848 | 0.85 | CTSK (0.54) | CTSKCTSLCTSSALDH1A1PREP | |
| SCHEMBL6235462 | 0.85 | CCR1 (0.46) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL6236601 | 0.85 | CTSK (0.48) | CTSKCTSLCTSSALDH1A1TSHR | |
| SCHEMBL4044041 | 0.85 | CTSK (0.43) | CTSKALDH1A1PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |