Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044561 | 0.90 | PPARG (0.50) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4043815 | 0.83 | PPARG (0.49) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4043725 | 0.80 | KDM4E (0.48) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4047340 | 0.79 | PPARG (0.44) | L3MBTL1ALDH1A1PPARGMAOBLMNA | |
| SCHEMBL4043269 | 0.77 | KDM4E (0.44) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4045889 | 0.74 | CACNA1B (0.43) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4048616 | 0.73 | MAOB (0.44) | HPGDKDM4EALDH1A1MAPK1MAOB | |
| SCHEMBL4048780 | 0.73 | ALDH1A1 (0.50) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4045394 | 0.73 | NOTUM (0.48) | HPGDL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4046143 | 0.73 | KDM4E (0.50) | HPGDL3MBTL1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603921-B1 | THIADIBENZOAZULENE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | GLAXOSMITHKLINE ZAGREB (HR) | 2009-06-17 | — | — | EP | claimed |