Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043160 | 0.94 | PPARG (0.43) | PPARGMAOBL3MBTL1LMNAMEN1 | |
| SCHEMBL4044561 | 0.85 | PPARG (0.50) | PPARGMAOBL3MBTL1LMNAMEN1 | |
| SCHEMBL4050340 | 0.84 | CACNA1B (0.42) | MAOBALDH1A1ESR1MAOA | |
| SCHEMBL6204224 | 0.83 | TYMS (0.37) | L3MBTL1MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL4045987 | 0.79 | HDAC3 (0.41) | MAOBMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL4043815 | 0.78 | PPARG (0.49) | PPARGMAOBL3MBTL1LMNAMEN1 | |
| SCHEMBL6204171 | 0.78 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1 | |
| SCHEMBL4051251 | 0.76 | ACHE (0.44) | MAOBESR1 | |
| SCHEMBL4048616 | 0.70 | MAOB (0.44) | MAOBHSP90AA1ALDH1A1MAOACA2 | |
| SCHEMBL4044517 | 0.70 | SLC6A4 (0.39) | MAOBMAOALTB4RLTB4R2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603921-B1 | THIADIBENZOAZULENE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | GLAXOSMITHKLINE ZAGREB (HR) | 2009-06-17 | — | — | EP | claimed |