Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044338 | 0.91 | CSNK1E (0.51) | AKR1C3CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL4041706 | 0.84 | CSNK1E (0.42) | KMT2ACSNK1E | |
| SCHEMBL14368458 | 0.80 | CSNK1E (0.65) | TSHRCSNK1E | |
| SCHEMBL6631721 | 0.76 | MEN1 (0.53) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL13963964 | 0.74 | CSNK1E (0.49) | CYP2C9CYP2C19TSHRALDH1A1CSNK1E | |
| SCHEMBL14368446 | 0.73 | CSNK1E (0.51) | CYP2C9CYP2C19CSNK1EHPGD | |
| SCHEMBL13964275 | 0.73 | CSNK1E (0.76) | CSNK1E | |
| SCHEMBL6658946 | 0.73 | P2RX7 (0.41) | CYP2C9KMT2ACSNK1E | |
| SCHEMBL4045067 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1KMT2ACSNK1ERAB9AHTT | |
| SCHEMBL14368444 | 0.71 | FAAH (0.49) | CSNK1ERAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | disclosed |