Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 14/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658946 | 0.87 | P2RX7 (0.41) | CSNK1EP2RX7KMT2AMEN1 | |
| SCHEMBL4044914 | 0.84 | AKR1C3 (0.47) | CSNK1EKMT2A | |
| SCHEMBL6631721 | 0.82 | MEN1 (0.53) | KMT2AMEN1 | |
| SCHEMBL6654811 | 0.81 | CSNK1E (0.39) | CSNK1EKMT2AMEN1 | |
| SCHEMBL4045126 | 0.77 | KMT2A (0.38) | CSNK1EKMT2AMEN1 | |
| SCHEMBL14368388 | 0.76 | CSNK1E (0.53) | CSNK1E | |
| SCHEMBL4042414 | 0.76 | CSNK1E (0.40) | CSNK1EP2RX7 | |
| SCHEMBL4041559 | 0.74 | CSNK1E (0.49) | CSNK1E | |
| SCHEMBL14368409 | 0.74 | CSNK1E (0.60) | CSNK1E | |
| SCHEMBL4038552 | 0.74 | CSNK1E (0.52) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | disclosed |
| CN-1556807-A | Chemical compounds | �㶫��������ҽҩ�ɷ�����˾ | 2004-12-22 | — | — | CN | disclosed |
| EP-1436291-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | Aventis Pharma S.A. (FR) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003024967-A2 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2003-03-27 | — | — | WO | disclosed |