Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.36 |
| ▸ | HTR3B | O95264 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043168 | 0.91 | CTSK (0.48) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4048979 | 0.89 | CTSK (0.55) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4051356 | 0.88 | CTSK (0.48) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4043626 | 0.88 | CTSK (0.48) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4042777 | 0.85 | CTSK (0.57) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4044153 | 0.84 | CTSK (0.70) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL8349299 | 0.84 | CTSK (0.70) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4045501 | 0.84 | CTSK (0.53) | CTSKHPGDSCTSSCTSBCTSL | |
| SCHEMBL4043015 | 0.83 | CTSK (0.55) | CTSKHPGDSCTSSCTSBACKR3 | |
| SCHEMBL4043391 | 0.83 | CTSK (0.55) | CTSKHPGDSCTSSCTSBACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |