Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.39 |
| ▸ | CTSK | P43235 | 19/20 | 0.39 |
| ▸ | CTSS | P25774 | 18/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047044 | 0.92 | CTSK (0.45) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4044872 | 0.92 | CTSK (0.44) | CTSLCTSKCTSSCTSBPREP | |
| SCHEMBL4042075 | 0.90 | PREP (0.36) | CTSLCTSKCTSSCTSBPREP | |
| SCHEMBL4042235 | 0.90 | PREP (0.36) | CTSLCTSKCTSSCTSBPREP | |
| SCHEMBL4046666 | 0.89 | HSD17B10 (0.36) | CTSKCTSSPREPFAP | |
| SCHEMBL4046918 | 0.87 | PREP (0.34) | CTSKPREPFAP | |
| SCHEMBL4048133 | 0.86 | PREP (0.34) | CTSKPREPFAP | |
| SCHEMBL4045110 | 0.86 | PREP (0.35) | CTSKCTSSCTSBPREPFAP | |
| SCHEMBL4050283 | 0.86 | PREP (0.35) | CTSKCTSSPREPFAP | |
| SCHEMBL4042489 | 0.86 | CTSK (0.40) | CTSLCTSKCTSSPREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |