Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.35 |
| ▸ | FAP | Q12884 | 4/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | MC1R | Q01726 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045238 | 0.93 | CTSK (0.42) | PREPFAPCTSKELANECTSS | |
| SCHEMBL4045687 | 0.92 | MC4R (0.34) | PREPFAPCTSKELANEMC4R | |
| SCHEMBL4046666 | 0.90 | HSD17B10 (0.36) | PREPFAPCTSKCTSSHCRTR2 | |
| SCHEMBL4042235 | 0.89 | PREP (0.36) | PREPFAPCTSKMC4RMC3R | |
| SCHEMBL4045110 | 0.88 | PREP (0.35) | PREPFAPCTSKCTSS | |
| SCHEMBL4051965 | 0.87 | MC4R (0.38) | CTSKELANEMC4RMC3RMC1R | |
| SCHEMBL4043596 | 0.86 | ELANE (0.38) | PREPFAPCTSKELANEMC4R | |
| SCHEMBL4045549 | 0.86 | CTSL (0.39) | PREPFAPCTSKCTSS | |
| SCHEMBL4044339 | 0.86 | ALDH1A1 (0.37) | PREPFAPCTSKELANEMC4R | |
| SCHEMBL4042570 | 0.85 | CTSK (0.34) | PREPFAPCTSKELANEMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |