Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041725 | 0.96 | CACNA1B (0.41) | HDAC3HDAC1HDAC2PDK2KDM4E | |
| SCHEMBL4050340 | 0.89 | CACNA1B (0.42) | HDAC3HDAC1HDAC2PDK2KDM4E | |
| SCHEMBL4043160 | 0.85 | PPARG (0.43) | ALDH1A1MEN1KMT2AHPGDMAOB | |
| SCHEMBL4048452 | 0.85 | MEN1 (0.43) | HDAC3HDAC1HDAC2PDK2KDM4E | |
| SCHEMBL4051251 | 0.84 | ACHE (0.44) | MAOBACHE | |
| SCHEMBL4046658 | 0.84 | CACNA1B (0.44) | HDAC3HDAC1HDAC2PDK2KDM4E | |
| SCHEMBL4044883 | 0.81 | CACNA1B (0.43) | HDAC3HDAC1HDAC2PDK2KDM4E | |
| SCHEMBL6204224 | 0.81 | TYMS (0.37) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4047340 | 0.79 | PPARG (0.44) | ALDH1A1MEN1KMT2AMAOBMAOA | |
| SCHEMBL5435148 | 0.77 | KDM4E (0.44) | HDAC3HDAC1HDAC2PDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603921-B1 | THIADIBENZOAZULENE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | GLAXOSMITHKLINE ZAGREB (HR) | 2009-06-17 | — | — | EP | claimed |