Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170196 | 0.78 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29374931 | 0.78 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30883995 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31365172 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30527876 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL34463709 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10866984 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL31243061 | 0.76 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31490600 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30883993 | 0.76 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589096-B2 | Azole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| EP-1566384-B1 | NOVEL AZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-20080188507-A1 | Novel azole derivatives | MSD K.K. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20080113957-A1 | Preparation and use of compounds as protease inhibitors | SCHERING CORPORATION | 2008-05-15 | — | — | US | disclosed |
| US-7365079-B2 | Azole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20060111380-A1 | Novel azole derivatives | MSD K.K. (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1566384-A1 | NOVEL AZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188507-A1 | Novel azole derivatives | NPY1R, NPY5R, NPY2R | RAB9A 2657/4885NPC1 4195/4885ALDH1A1 2656/4885 |
| US-20060111380-A1 | Novel azole derivatives | NPY1R, NPY5R, NPY2R | RAB9A 2739/4885NPC1 4203/4885ALDH1A1 2382/4885 |
| US-20080113957-A1 | Preparation and use of compounds as protease inhibitors | PRSS1, BCHE, PRSS3 | RAB9A 3175/4885NPC1 481/4885ALDH1A1 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.