Dimethylformamide

Dimethylformamide

SCHEMBL4046504

CN(C)C=O.CN(C)P(=O)(F)N(C)C

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118899 0.84
SCHEMBL6739890 0.84
Isobutyramide SCHEMBL9732728 0.81 TSHR (0.35) TSHR
Water SCHEMBL29412656 0.81
Dimethylformamide SCHEMBL3284756 0.75 TSHR (0.60) TSHRUSP2ALOX15
Benzene SCHEMBL5152353 0.75 HTT (0.38)
Dimethylformamide SCHEMBL1927321 0.73 TSHR (1.00) TSHRUSP2ALOX15
Dimethylformamide SCHEMBL10141201 0.73
Dimethylformamide SCHEMBL5 0.73
Dimethylformamide SCHEMBL1332179 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220024899-A1 BI-FUNCTIONAL NANOHYBRIDS SON (FR) 2022-01-27 US disclosed
EP-3897977-A1 BI-FUNCTIONAL NANOHYBRIDS SON (FR) 2021-10-27 EP disclosed
WO-2020127644-A1 BI-FUNCTIONAL NANOHYBRIDS UNIVERSITE DE BOURGOGNE (FR) 2020-06-25 WO disclosed
CN-107107546-B Moisture-permeability waterproof fabric and its manufacturing method 阿莫绿色技术有限公司 2019-11-05 CN disclosed
CN-108884058-A MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS 阿奇克斯制药公司 2018-11-23 CN disclosed
CN-108831999-A A kind of preparation method of accuracy controlling perovskite thin film crystallite dimension 南京邮电大学 2018-11-16 CN disclosed
CN-108832003-A A method of improving perovskite solar cell photoelectric transfer efficiency 南京邮电大学 2018-11-16 CN disclosed
CN-108780843-A Semiconductor element, its manufacturing method, wireless communication device and sensor 东丽株式会社 2018-11-09 CN disclosed
CN-104984372-B Radioconjugation method 通用电气健康护理有限公司 2018-11-09 CN disclosed
CN-106573898-B Treat and prevent hepatitis b virus infected new pyridazinone and triazinone 豪夫迈·罗氏有限公司 2018-11-09 CN disclosed
US-20020115685-A1 Novel N-(arylsulphonyl) amino acid derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI-AVENTIS (FR) 2002-08-22 US disclosed
US-6420375-B1 ANTITUMOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-16 US disclosed
WO-2002018327-A2 GUANIDINOBENZAMIDES AS MC4-R AGONISTS CHIRON CORPORATION (US) 2002-03-07 WO disclosed
CN-1072210-C 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors SANOFI SYNTHELABO (FR) 2001-10-03 CN disclosed
EP-0787115-B1 PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO[3a,3,2-ef][2]BENZAZEPINE SANOCHEMIA PHARMAZEUTIKA AG (AT) 2000-01-05 EP disclosed
CN-1038748-C Method for preparing sulfonamide fibrinogen receptor antagonists MERCK & CO INC (US) 1998-06-17 CN disclosed
US-5284661-A 4-Oxo-7-(biphenyl-4-yl)thieno(2,3-b)pyridines as antagonist of angiotensin II; hypertensive agents, cardiovascular disorders and strokes TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-02-08 US disclosed
US-5128366-A Enzyme inhibitors, anticholesterol SHINOGI & CO., LTD. (JP) 1992-07-07 US disclosed
US-5095139-A Fungicides CIBA-GEIGY CORPORATION (US) 1992-03-10 US disclosed
EP-0246795-A2 Synthetic natriuretic peptides ADVANCED PEPTIDE DEVELOPMENT LIMITED (GB) 1987-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115685-A1 Novel N-(arylsulphonyl) amino acid derivatives, process for their preparation and pharmaceutical compositions containing them CYP2C9, ADRM1, ADRA1D TSHR 2697/4885USP2 2707/4885ALOX15 1768/4885
US-20220024899-A1 BI-FUNCTIONAL NANOHYBRIDS MPO, DNMT1, CAT TSHR 4185/4885USP2 587/4885ALOX15 3155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.