Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050093 | 0.93 | HTT (0.41) | HTTRECQLELOVL6HSD17B10KCNQ1 | |
| SCHEMBL4050939 | 0.90 | CTSK (0.37) | HTTRECQLCTSKPOLBTSHR | |
| SCHEMBL4039972 | 0.90 | CTSK (0.40) | HTTRECQLCTSKPOLBTSHR | |
| SCHEMBL4040677 | 0.89 | CTSK (0.41) | ELOVL6CTSKHSD17B10KCNQ1HCRTR2 | |
| SCHEMBL4047459 | 0.88 | CTSK (0.38) | CTSKKCNQ1TSHRLMNAALDH1A1 | |
| SCHEMBL4051777 | 0.87 | CTSK (0.44) | ELOVL6CTSKHSD17B10KCNQ1HCRTR2 | |
| SCHEMBL4045230 | 0.87 | CTSK (0.43) | ELOVL6CTSK | |
| SCHEMBL4045961 | 0.86 | CTSK (0.39) | ELOVL6CTSKHSD17B10KCNQ1HCRTR2 | |
| SCHEMBL4049970 | 0.86 | CTSK (0.40) | ELOVL6CTSKHSD17B10KCNQ1HCRTR2 | |
| SCHEMBL4050084 | 0.85 | CTSK (0.41) | CTSKPOLBTSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |