Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051241 | 0.95 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL4052252 | 0.87 | KDM4C (0.41) | PI4KAPI4K2BPI4K2API4KBCCNB2 | |
| SCHEMBL4053122 | 0.80 | GPR84 (0.47) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL4046994 | 0.80 | ADORA1 (0.42) | CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL4044144 | 0.77 | METAP2 (0.34) | PI4KAPI4K2BPI4K2API4KBHCAR2 | |
| SCHEMBL4042151 | 0.76 | AAK1 (0.40) | GPR84 | |
| SCHEMBL246326 | 0.76 | PDE5A (0.53) | PI4KAPI4K2BPI4K2API4KBHCAR2 | |
| SCHEMBL4047518 | 0.76 | METAP2 (0.33) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9648738 | 0.74 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL9406720 | 0.73 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029592-A1 | HETEROBICYCLIC-SUBSTITUTED QUINOLONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |