Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047153 | 1.00 | ATM (0.39) | ATMALDH1A1HRH3KCNH2KDM1A | |
| SCHEMBL999798 | 1.00 | ATM (0.39) | ATMALDH1A1HRH3KCNH2KDM1A | |
| SCHEMBL4055784 | 1.00 | ATM (0.39) | ATMALDH1A1HRH3KCNH2KDM1A | |
| SCHEMBL16521122 | 0.79 | ALDH1A1 (0.35) | ATMALDH1A1HRH3KCNH2KDM1A | |
| SCHEMBL28513108 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1KDM1ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8660338 | 0.72 | ATM (0.48) | ATMALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL30561555 | 0.72 | ATM (0.48) | ATMALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL8517882 | 0.72 | ATM (0.48) | ATMALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL20109304 | 0.72 | ATM (0.34) | ATMALDH1A1HRH3KCNH2KDM1A | |
| SCHEMBL16001322 | 0.70 | ATM (0.47) | ATMALDH1A1NPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461315-B1 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2009-07-29 | — | — | EP | disclosed |
| US-6852865-B2 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | LOX, CA9, LPO | ATM 3279/4885ALDH1A1 1604/4885HRH3 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.