Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.40 |
| ▸ | CTSL | P07711 | 12/20 | 0.38 |
| ▸ | CTSS | P25774 | 10/20 | 0.38 |
| ▸ | CTSB | P07858 | 6/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042075 | 0.93 | PREP (0.36) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4045950 | 0.92 | CTSK (0.43) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4047044 | 0.90 | CTSK (0.45) | CTSKCTSLCTSSCTSBGRN | |
| SCHEMBL4046952 | 0.89 | CTSK (0.39) | CTSKCTSLCTSSCTSBGRN | |
| SCHEMBL4053835 | 0.88 | CTSK (0.40) | CTSKCTSLCTSSCTSBGRN | |
| SCHEMBL4051956 | 0.86 | CTSK (0.41) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4045311 | 0.86 | CTSK (0.43) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4039158 | 0.85 | CTSK (0.40) | CTSKCTSLCTSSCTSBGRN | |
| SCHEMBL4046882 | 0.85 | CTSK (0.41) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL4041598 | 0.85 | CTSK (0.40) | CTSKCTSLCTSSCTSBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |