Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045110 | 0.93 | PREP (0.35) | CTSKCTSSCTSBSMYD3FKBP1A | |
| SCHEMBL4051166 | 0.92 | CTSK (0.39) | CTSKCTSLCTSSCTSBFKBP1A | |
| SCHEMBL4039158 | 0.90 | CTSK (0.40) | CTSKGRNSORT1CTSLCTSS | |
| SCHEMBL4047618 | 0.89 | CTSK (0.40) | CTSKGRNSORT1CTSLCTSS | |
| SCHEMBL4045238 | 0.88 | CTSK (0.42) | CTSKGRNSORT1CTSLCTSS | |
| SCHEMBL4048898 | 0.87 | CTSK (0.43) | CTSKGRNSORT1CTSLCTSS | |
| SCHEMBL4050147 | 0.86 | CTSK (0.40) | CTSKCTSLCTSSCTSBSMYD3 | |
| SCHEMBL4043952 | 0.86 | CTSK (0.42) | CTSKCTSLCTSSCTSBFKBP1A | |
| SCHEMBL4047044 | 0.86 | CTSK (0.45) | CTSKGRNSORT1CTSLCTSS | |
| SCHEMBL4041373 | 0.85 | CTSK (0.38) | CTSKCTSLCTSSCTSBSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |