Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302294 | 0.86 | KDM4E (0.39) | CA2CA4KDM4EALDH1A1MEN1 | |
| SCHEMBL31444061 | 0.86 | KDM4E (0.39) | CA2CA4KDM4EALDH1A1MEN1 | |
| SCHEMBL5090600 | 0.81 | NQO2 (0.41) | NQO2CA2CA4ALOX5APFEN1 | |
| SCHEMBL127769 | 0.81 | CA2 (0.55) | NQO2CA2CA4ALOX5APFEN1 | |
| SCHEMBL8900747 | 0.71 | MAOA (0.38) | — | |
| SCHEMBL4922559 | 0.70 | CA2 (0.44) | NQO2CA2CA4ALOX5APFEN1 | |
| SCHEMBL30171329 | 0.70 | CA2 (0.50) | NQO2CA2CA4TUBB1TUBB4A | |
| SCHEMBL772484 | 0.70 | CA2 (0.50) | NQO2CA2CA4TUBB1TUBB4A | |
| SCHEMBL7219358 | 0.69 | KDM4E (0.50) | NQO2CA2CA4ALOX5APFEN1 | |
| SCHEMBL6423974 | 0.69 | CA2 (0.54) | NQO2CA2CA4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027679-A1 | PROCESS FOR THE PREPARATION OF GUANIDINO SUBSTITUTED BI-AND POLYPHENYLS THAT ARE SUITABLE AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2009-03-05 | — | — | WO | disclosed |