SCHEMBL4048252

SCHEMBL4048252

Fc1nc(Cl)c(F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2088817 0.83 KEAP1 (0.32)
SCHEMBL7034473 0.79
SCHEMBL8800638 0.77 PDE10A (0.31)
SCHEMBL188694 0.75 MEN1 (0.41)
SCHEMBL3146554 0.75
SCHEMBL1658541 0.75 PDE10A (0.30)
SCHEMBL9320239 0.73 MEN1 (0.32)
SCHEMBL8581211 0.73
SCHEMBL5635013 0.73 ALDH1A1 (0.39)
SCHEMBL10741693 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351528-B2 Tetrafluorosulfanylpyridine UBE INDUSTRIES, LTD. (JP) 2019-07-16 US disclosed
US-20180339969-A1 TETRAFLUOROSULFANYLPYRIDINE UBE CORPORATION (JP) 2018-11-29 US disclosed
EP-3381902-A1 TETRAFLUOROSULFANYLPYRIDINE UBE Industries, Ltd. (JP) 2018-10-03 EP disclosed
US-10040819-B2 Chemically modifying peptides THE UNIVERSITY OF DURHAM (GB) 2018-08-07 US disclosed
US-10040819-B2 Chemically modifying peptides THE UNIVERSITY OF DURHAM (GB) 2018-08-07 US disclosed
US-20170081360-A1 Chemically Modifying Peptides THE UNIVERSITY OF DURHAM (GB) 2017-03-23 US disclosed
US-20170081360-A1 Chemically Modifying Peptides THE UNIVERSITY OF DURHAM (GB) 2017-03-23 US disclosed
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 EP disclosed
US-6995110-B2 Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-07 US disclosed
US-20040077487-A1 Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-22 US disclosed
EP-1380342-A1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-01-14 EP disclosed
EP-1006135-B1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN IND LTD (JP) 2003-02-12 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed