Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049127 | 0.81 | HDAC1 (0.34) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL4416660 | 0.81 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL4048617 | 0.81 | KDM4E (0.43) | — | |
| SCHEMBL4048868 | 0.76 | ADORA3 (0.41) | HDAC1HDAC6 | |
| SCHEMBL4048878 | 0.76 | HDAC1 (0.33) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL22501426 | 0.75 | HDAC3 (0.61) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL2073773 | 0.74 | HDAC1 (0.73) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL4055945 | 0.73 | ALDH1A1 (0.41) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL4163303 | 0.73 | HDAC1 (0.60) | HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL2073554 | 0.72 | HDAC1 (0.76) | HDAC1HDAC2HDAC3HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |