Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070917 | 0.81 | HDAC1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL4048438 | 0.81 | HDAC1 (0.52) | — | |
| SCHEMBL4932013 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1CNR1HPGDSMN1; SMN2 | |
| SCHEMBL2346474 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1CNR1HPGDSMN1; SMN2 | |
| SCHEMBL1927026 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1CNR1HPGDSMN1; SMN2 | |
| SCHEMBL4048878 | 0.77 | HDAC1 (0.33) | ALDH1A1 | |
| SCHEMBL4048868 | 0.77 | ADORA3 (0.41) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4055945 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL4049127 | 0.72 | HDAC1 (0.34) | — | |
| SCHEMBL4056394 | 0.70 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |