Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057361 | 0.89 | GPR119 (0.45) | GPR119FAAHPGRCYP2D6CYP2C9 | |
| SCHEMBL4048769 | 0.85 | JAK2 (0.48) | GPR119 | |
| SCHEMBL13690325 | 0.81 | FAAH (0.33) | FAAH | |
| SCHEMBL13690504 | 0.80 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4050169 | 0.80 | GPR119 (0.57) | GPR119 | |
| SCHEMBL13690402 | 0.79 | GPR119 (0.46) | GPR119 | |
| SCHEMBL4048482 | 0.79 | GPR119 (0.56) | GPR119 | |
| SCHEMBL4048819 | 0.79 | GPR119 (0.40) | GPR119 | |
| SCHEMBL13690725 | 0.78 | L3MBTL3 (0.46) | — | |
| SCHEMBL13690401 | 0.78 | GPR119 (0.48) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |