Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397520 | 0.86 | L3MBTL1 (0.48) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2106701 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1427472 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL3397376 | 0.79 | GFER (0.51) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4289837 | 0.79 | CHKA (0.55) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL2800744 | 0.79 | CYP2A13 (0.51) | KDM4EALDH1A1MEN1KMT2ACYP2A13 | |
| SCHEMBL3637621 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2ACYP2A13 | |
| SCHEMBL2574046 | 0.76 | KMT2A (0.42) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4293427 | 0.75 | MBTD1 (0.41) | KDM4EALDH1A1L3MBTL1POLB | |
| SCHEMBL4287610 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066647-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | Novartis AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008031594-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |