Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68851 | 0.76 | CYP4Z1 (0.62) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL512626 | 0.76 | CYP4Z1 (0.55) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL11077525 | 0.74 | CYP4Z1 (0.54) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL4052194 | 0.74 | CYP4F2 (0.50) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17316726 | 0.73 | CYP4Z1 (0.52) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL10798505 | 0.72 | CYP4F2 (0.56) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL184705 | 0.72 | CYP4Z1 (0.54) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL1809809 | 0.72 | CYP4Z1 (0.54) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL68930 | 0.71 | CYP4Z1 (0.57) | CYP4Z1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL6057577 | 0.71 | CYP4F2 (0.59) | CYP4Z1MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |