Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113212 | 0.77 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL7360766 | 0.76 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL11543446 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GAAPOLBSMN1; SMN2NPC1 | |
| SCHEMBL11150730 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAAPOLBSMN1; SMN2NPC1 | |
| SCHEMBL4049114 | 0.74 | CYP4Z1 (0.49) | CYP4F2CYP4A11ALDH1A1GAAPOLB | |
| SCHEMBL11550075 | 0.73 | TDP1 (0.40) | ALDH1A1GAAGFERPOLBSMN1; SMN2 | |
| SCHEMBL11372476 | 0.72 | LMNA (0.42) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8862126 | 0.72 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL166999 | 0.72 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL8111448 | 0.72 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |