Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485170 | 0.86 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL3197591 | 0.86 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL534910 | 0.84 | CHRM5 (0.50) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL17474538 | 0.83 | CHRM5 (0.60) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL14919952 | 0.81 | CHRM5 (0.56) | SLC6A3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL4756289 | 0.78 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL3987591 | 0.77 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL3982599 | 0.76 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL5731017 | 0.73 | CHRM5 (0.48) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL3194232 | 0.73 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109608-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-09-11 | — | — | WO | disclosed |